In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo; Hyejung Lee; Sojin Lee; Kyung Hyun Min; Min Sang Kim; Doo Sung Lee; Yongseok Choi; Ick Chan Kwon; Kwangmeyung Kim; Seo Young Jeong

doi:10.1039/c0cc01413c

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo
, Hyejung Lee
, Sojin Lee
, Kyung Hyun Min
, Min Sang Kim
, Doo Sung Lee
, Yongseok Choi
, Ick Chan Kwon
, Kwangmeyung Kim
, Seo Young Jeong

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

186 Scopus citations

Abstract

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

Original language	English
Pages (from-to)	5668-5670
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	31
DOIs	https://doi.org/10.1039/c0cc01413c
State	Published - 21 Aug 2010

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1039/c0cc01413c

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title = "In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles",

abstract = "We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.",

author = "Heebeom Koo and Hyejung Lee and Sojin Lee and Min, \{Kyung Hyun\} and Kim, \{Min Sang\} and Lee, \{Doo Sung\} and Yongseok Choi and Kwon, \{Ick Chan\} and Kwangmeyung Kim and Jeong, \{Seo Young\}",

year = "2010",

month = aug,

day = "21",

doi = "10.1039/c0cc01413c",

language = "English",

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pages = "5668--5670",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

AU - Koo, Heebeom

AU - Lee, Hyejung

AU - Lee, Sojin

AU - Min, Kyung Hyun

AU - Kim, Min Sang

AU - Lee, Doo Sung

AU - Choi, Yongseok

AU - Kwon, Ick Chan

AU - Kim, Kwangmeyung

AU - Jeong, Seo Young

PY - 2010/8/21

Y1 - 2010/8/21

N2 - We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

AB - We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

UR - https://www.scopus.com/pages/publications/77955209935

U2 - 10.1039/c0cc01413c

DO - 10.1039/c0cc01413c

M3 - Article

C2 - 20623050

AN - SCOPUS:77955209935

SN - 1359-7345

VL - 46

SP - 5668

EP - 5670

JO - Chemical Communications

JF - Chemical Communications

IS - 31

ER -

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Abstract

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