In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo; Hyejung Lee; Sojin Lee; Kyung Hyun Min; Min Sang Kim; Doo Sung Lee; Yongseok Choi; Ick Chan Kwon; Kwangmeyung Kim; Seo Young Jeong

doi:10.1039/c0cc01413c

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Heebeom Koo, Hyejung Lee, Sojin Lee, Kyung Hyun Min, Min Sang Kim, Doo Sung Lee, Yongseok Choi, Ick Chan Kwon, Kwangmeyung Kim, Seo Young Jeong

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

180 Scopus citations

Abstract

We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

Original language	English
Pages (from-to)	5668-5670
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	31
DOIs	https://doi.org/10.1039/c0cc01413c
State	Published - 21 Aug 2010

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title = "In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles",

abstract = "We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.",

author = "Heebeom Koo and Hyejung Lee and Sojin Lee and Min, {Kyung Hyun} and Kim, {Min Sang} and Lee, {Doo Sung} and Yongseok Choi and Kwon, {Ick Chan} and Kwangmeyung Kim and Jeong, {Seo Young}",

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doi = "10.1039/c0cc01413c",

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T1 - In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

AU - Koo, Heebeom

AU - Lee, Hyejung

AU - Lee, Sojin

AU - Min, Kyung Hyun

AU - Kim, Min Sang

AU - Lee, Doo Sung

AU - Choi, Yongseok

AU - Kwon, Ick Chan

AU - Kim, Kwangmeyung

AU - Jeong, Seo Young

PY - 2010/8/21

Y1 - 2010/8/21

N2 - We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

AB - We report protoporphyrin IX (PpIX) encapsulated pH-responsive micelles for cancer treatment. This system showed pH-responsive micellization/demicellization transition at tumoral acidic pH and enabled in vivo tumor diagnosis and therapy simultaneously.

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U2 - 10.1039/c0cc01413c

DO - 10.1039/c0cc01413c

M3 - Article

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AN - SCOPUS:77955209935

SN - 1359-7345

VL - 46

SP - 5668

EP - 5670

JO - Chemical Communications

JF - Chemical Communications

IS - 31

ER -

In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles

Abstract

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