Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents

Hanyong Kim; Hah Young Yoo; Yong Hwan Ki; Il Kwon Kim; Eui Hong Byun; Yung Hun Yang; Si Jae Park; Jeong Geol Na; Hiesang Sohn; Taek Lee; Jung Rae Kim; Chulhwan Park

doi:10.1007/s11814-018-0075-z

Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents

Hanyong Kim, Hah Young Yoo, Yong Hwan Ki, Il Kwon Kim, Eui Hong Byun, Yung Hun Yang, Si Jae Park, Jeong Geol Na, Hiesang Sohn, Taek Lee, Jung Rae Kim, Chulhwan Park

Department of Chemical Engineering & Materials Science

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.

Original language	English
Pages (from-to)	1854-1859
Number of pages	6
Journal	Korean Journal of Chemical Engineering
Volume	35
Issue number	9
DOIs	https://doi.org/10.1007/s11814-018-0075-z
State	Published - 1 Sep 2018

Bibliographical note

Funding Information:
This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2016R1D1A1A09918327), the C1 Gas Refinery Program through NRF funded by the Ministry of Science and ICT (NRF-2018M3D3A1A01017991).

Publisher Copyright:
© 2018, Korean Institute of Chemical Engineers, Seoul, Korea.

Keywords

1,5-Diaminopentane
Cadaverine
Decarboxylation
Detergent
Hafnia alvei
Lysine

Access to Document

10.1007/s11814-018-0075-z

Cite this

Kim, H., Yoo, H. Y., Ki, Y. H., Kim, I. K., Byun, E. H., Yang, Y. H., Park, S. J., Na, J. G., Sohn, H., Lee, T., Kim, J. R., & Park, C. (2018). Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents. Korean Journal of Chemical Engineering, 35(9), 1854-1859. https://doi.org/10.1007/s11814-018-0075-z

@article{03bb619a492d451a9e39e7bdecaf7121,

title = "Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents",

abstract = "World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.",

keywords = "1,5-Diaminopentane, Cadaverine, Decarboxylation, Detergent, Hafnia alvei, Lysine",

author = "Hanyong Kim and Yoo, {Hah Young} and Ki, {Yong Hwan} and Kim, {Il Kwon} and Byun, {Eui Hong} and Yang, {Yung Hun} and Park, {Si Jae} and Na, {Jeong Geol} and Hiesang Sohn and Taek Lee and Kim, {Jung Rae} and Chulhwan Park",

note = "Funding Information: This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2016R1D1A1A09918327), the C1 Gas Refinery Program through NRF funded by the Ministry of Science and ICT (NRF-2018M3D3A1A01017991). Publisher Copyright: {\textcopyright} 2018, Korean Institute of Chemical Engineers, Seoul, Korea.",

year = "2018",

month = sep,

day = "1",

doi = "10.1007/s11814-018-0075-z",

language = "English",

volume = "35",

pages = "1854--1859",

journal = "Korean Journal of Chemical Engineering",

issn = "0256-1115",

publisher = "Springer New York",

number = "9",

}

Kim, H, Yoo, HY, Ki, YH, Kim, IK, Byun, EH, Yang, YH, Park, SJ, Na, JG, Sohn, H, Lee, T, Kim, JR & Park, C 2018, 'Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents', Korean Journal of Chemical Engineering, vol. 35, no. 9, pp. 1854-1859. https://doi.org/10.1007/s11814-018-0075-z

TY - JOUR

T1 - Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents

AU - Kim, Hanyong

AU - Yoo, Hah Young

AU - Ki, Yong Hwan

AU - Kim, Il Kwon

AU - Byun, Eui Hong

AU - Yang, Yung Hun

AU - Park, Si Jae

AU - Na, Jeong Geol

AU - Sohn, Hiesang

AU - Lee, Taek

AU - Kim, Jung Rae

AU - Park, Chulhwan

N1 - Funding Information: This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2016R1D1A1A09918327), the C1 Gas Refinery Program through NRF funded by the Ministry of Science and ICT (NRF-2018M3D3A1A01017991). Publisher Copyright: © 2018, Korean Institute of Chemical Engineers, Seoul, Korea.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.

AB - World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.

KW - 1,5-Diaminopentane

KW - Cadaverine

KW - Decarboxylation

KW - Detergent

KW - Hafnia alvei

KW - Lysine

UR - http://www.scopus.com/inward/record.url?scp=85050334552&partnerID=8YFLogxK

U2 - 10.1007/s11814-018-0075-z

DO - 10.1007/s11814-018-0075-z

M3 - Article

AN - SCOPUS:85050334552

SN - 0256-1115

VL - 35

SP - 1854

EP - 1859

JO - Korean Journal of Chemical Engineering

JF - Korean Journal of Chemical Engineering

IS - 9

ER -

Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this