Implantable optical neural interface

Sang Beom Jun, Yoonseob Lim

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


For more than several decades, due to the rapid development of sophisticated electronics, the electrical neural interface has become the most popular method for recording and modulating neural activity in nerve systems. The electrical neural interface has been successfully applied to implantable neural prosthetic systems such as cochlear implant, deep brain stimulation system, artificial retina, and so on. Recently, in order to overcome the limitations of electrical methods for neural interface, novel optical technologies have been developed and applied to neuroscience research. Overall, the optical neural interfaces can be categorized into the intrinsic and the extrinsic methods depending on the modification of natural nerve system. For example, infrared neural stimulation (INS) and optogenetic neural stimulation are the typical methods for intrinsic and extrinsic neural interfaces, respectively. In addition to the optogenetic stimulation, it is also possible to monitor neural activity from specific neurons genetically modified to express activity-correlated fluorescence signals. Therefore, the optogenetic neural recording enables the detection of activity from specific types of neurons. Despite the fascinating advantages, to date, the use of the optical neural interface is limited only to the neuroscience research not for clinical purposes. In this chapter, the state-ofart technologies in optical neural interface are reviewed from the aspects of both neurobiology and engineering. In addition, the challenges to realize the clinical use of optical neural interfaces are discussed.

Original languageEnglish
Title of host publicationSmart Sensors and Systems
Subtitle of host publicationInnovations for Medical, Environmental, and IoT Applications
PublisherSpringer International Publishing
Number of pages28
ISBN (Electronic)9783319332017
ISBN (Print)9783319332000
StatePublished - 1 Jan 2016

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2017.


  • Infrared neural stimulation
  • Optical neural interface
  • Optogenetics


Dive into the research topics of 'Implantable optical neural interface'. Together they form a unique fingerprint.

Cite this