Impact of Prenatal Cocaine Exposure on Adolescent Behavior

M. O. Min, S. Minnes, S. Yoon, L. T. Singer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations


This chapter discusses the effects of prenatal cocaine exposure (PCE) on three adolescent behavioral outcomes: internalizing and externalizing behavior, substance use, and sexual risk behavior. Various studies from multiple longitudinal prospective birth cohorts collectively indicate that PCE is related to greater externalizing behavior problems and early onset of substance use and sexual behavior, after controlling for biological and environmental confounders such as prenatal exposure to other substances, lead exposure, suboptimal caregiving environment, and violence exposure. Less is known about the underlying mechanisms (i.e., indirect effects of PCE), gender differences (i.e., PCE by gender interaction), or the role of life stress in the link between PCE and adolescent behavioral outcomes, warranting further investigation. Continued studies into adulthood will also elucidate whether the behavioral problems and early indications of substance use and sexual risk behavior persist through early adulthood and affect social and vocational adjustment.

Original languageEnglish
Title of host publicationThe Neuroscience of Cocaine
Subtitle of host publicationMechanisms and Treatment
PublisherElsevier Inc.
Number of pages10
ISBN (Electronic)9780128037928
ISBN (Print)9780128037508
StatePublished - 16 May 2017

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Inc. All rights reserved.


  • Adolescent
  • Behavior
  • High-risk population
  • Prenatal cocaine exposure
  • Sexual risk
  • Substance use


Dive into the research topics of 'Impact of Prenatal Cocaine Exposure on Adolescent Behavior'. Together they form a unique fingerprint.

Cite this