Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3

Jongmin Park; Jung In Um; Ala Jo; Jinho Lee; Da Woon Jung; Darren R. Williams; Seung Bum Park

doi:10.1039/c4cc00955j

Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3

Jongmin Park, Jung In Um, Ala Jo, Jinho Lee, Da Woon Jung, Darren R. Williams, Seung Bum Park

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

The molecular charge of fluorescent bioprobes has recently received much attention due to its influence on cellular uptake. Herein, we demonstrate the effect of the molecular charge of glucose bioprobes on their GLUT-specific cellular uptake. We also applied GB2-Cy3 to in vivo imaging in the zebrafish model.

Original language	English
Pages (from-to)	9251-9254
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	60
DOIs	https://doi.org/10.1039/c4cc00955j
State	Published - 22 Jul 2014

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title = "Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3",

abstract = "The molecular charge of fluorescent bioprobes has recently received much attention due to its influence on cellular uptake. Herein, we demonstrate the effect of the molecular charge of glucose bioprobes on their GLUT-specific cellular uptake. We also applied GB2-Cy3 to in vivo imaging in the zebrafish model.",

author = "Jongmin Park and Um, \{Jung In\} and Ala Jo and Jinho Lee and Jung, \{Da Woon\} and Williams, \{Darren R.\} and Park, \{Seung Bum\}",

year = "2014",

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doi = "10.1039/c4cc00955j",

language = "English",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3

AU - Park, Jongmin

AU - Um, Jung In

AU - Jo, Ala

AU - Lee, Jinho

AU - Jung, Da Woon

AU - Williams, Darren R.

AU - Park, Seung Bum

PY - 2014/7/22

Y1 - 2014/7/22

N2 - The molecular charge of fluorescent bioprobes has recently received much attention due to its influence on cellular uptake. Herein, we demonstrate the effect of the molecular charge of glucose bioprobes on their GLUT-specific cellular uptake. We also applied GB2-Cy3 to in vivo imaging in the zebrafish model.

AB - The molecular charge of fluorescent bioprobes has recently received much attention due to its influence on cellular uptake. Herein, we demonstrate the effect of the molecular charge of glucose bioprobes on their GLUT-specific cellular uptake. We also applied GB2-Cy3 to in vivo imaging in the zebrafish model.

UR - https://www.scopus.com/pages/publications/84904729631

U2 - 10.1039/c4cc00955j

DO - 10.1039/c4cc00955j

M3 - Article

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AN - SCOPUS:84904729631

SN - 1359-7345

VL - 50

SP - 9251

EP - 9254

JO - Chemical Communications

JF - Chemical Communications

IS - 60

ER -

Impact of molecular charge on GLUT-specific cellular uptake of glucose bioprobes and in vivo application of the glucose bioprobe, GB2-Cy3

Abstract

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