Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

Chi Min Park; Younsuck Koh; Kyeongman Jeon; Sungwon Na; Chae Man Lim; Won Il Choi; Young Joo Lee; Seok Chan Kim; Gyu Rak Chon; Je Hyeong Kim; Jae Yeol Kim; Jaemin Lim; Chin Kook Rhee; Sunghoon Park; Ho Cheol Kim; Jin Hwa Lee; Ji Hyun Lee; Jisook Park; Juhee Cho; Shin Ok Koh; Gee Young Suh; So Yeon Lim; Sang Bum Hong; Jin Won Huh; Suk Kyung Hong; Won Il Choi; Kwang Joo Park; Chan Kwon Park; Ick Hee Kim; Ho Cheol Kim; Hyun Lee; Jae Hwa Cho

doi:10.1016/j.jcrc.2014.01.016

Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

Chi Min Park, Younsuck Koh, Kyeongman Jeon, Sungwon Na, Chae Man Lim, Won Il Choi, Young Joo Lee, Seok Chan Kim, Gyu Rak Chon, Je Hyeong Kim, Jae Yeol Kim, Jaemin Lim, Chin Kook Rhee, Sunghoon Park, Ho Cheol Kim, Jin Hwa Lee, Ji Hyun Lee, Jisook Park, Juhee Cho, Shin Ok KohGee Young Suh, So Yeon Lim, Sang Bum Hong, Jin Won Huh, Suk Kyung Hong, Won Il Choi, Kwang Joo Park, Chan Kwon Park, Ick Hee Kim, Ho Cheol Kim, Hyun Lee, Jae Hwa Cho

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.

Original language	English
Pages (from-to)	409-413
Number of pages	5
Journal	Journal of Critical Care
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/j.jcrc.2014.01.016
State	Published - Jun 2014

Keywords

Hospital mortality
Intensive care
Performance status
Prognosis

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10.1016/j.jcrc.2014.01.016

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Park, C. M., Koh, Y., Jeon, K., Na, S., Lim, C. M., Choi, W. I., Lee, Y. J., Kim, S. C., Chon, G. R., Kim, J. H., Kim, J. Y., Lim, J., Rhee, C. K., Park, S., Kim, H. C., Lee, J. H., Lee, J. H., Park, J., Cho, J., ... Cho, J. H. (2014). Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients. Journal of Critical Care, 29(3), 409-413. https://doi.org/10.1016/j.jcrc.2014.01.016

@article{983d6d825c1b420cb78e8aaeb074292a,

title = "Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients",

abstract = "Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.",

keywords = "Hospital mortality, Intensive care, Performance status, Prognosis",

author = "Park, {Chi Min} and Younsuck Koh and Kyeongman Jeon and Sungwon Na and Lim, {Chae Man} and Choi, {Won Il} and Lee, {Young Joo} and Kim, {Seok Chan} and Chon, {Gyu Rak} and Kim, {Je Hyeong} and Kim, {Jae Yeol} and Jaemin Lim and Rhee, {Chin Kook} and Sunghoon Park and Kim, {Ho Cheol} and Lee, {Jin Hwa} and Lee, {Ji Hyun} and Jisook Park and Juhee Cho and Koh, {Shin Ok} and Suh, {Gee Young} and Lim, {So Yeon} and Hong, {Sang Bum} and Huh, {Jin Won} and Hong, {Suk Kyung} and Choi, {Won Il} and Park, {Kwang Joo} and Park, {Chan Kwon} and Kim, {Ick Hee} and Kim, {Ho Cheol} and Hyun Lee and Cho, {Jae Hwa}",

year = "2014",

month = jun,

doi = "10.1016/j.jcrc.2014.01.016",

language = "English",

volume = "29",

pages = "409--413",

journal = "Journal of Critical Care",

issn = "0883-9441",

publisher = "Elsevier BV",

number = "3",

}

Park, CM, Koh, Y, Jeon, K, Na, S, Lim, CM, Choi, WI, Lee, YJ, Kim, SC, Chon, GR, Kim, JH, Kim, JY, Lim, J, Rhee, CK, Park, S, Kim, HC, Lee, JH, Lee, JH, Park, J, Cho, J, Koh, SO, Suh, GY, Lim, SY, Hong, SB, Huh, JW, Hong, SK, Choi, WI, Park, KJ, Park, CK, Kim, IH, Kim, HC, Lee, H & Cho, JH 2014, 'Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients', Journal of Critical Care, vol. 29, no. 3, pp. 409-413. https://doi.org/10.1016/j.jcrc.2014.01.016

TY - JOUR

T1 - Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

AU - Park, Chi Min

AU - Koh, Younsuck

AU - Jeon, Kyeongman

AU - Na, Sungwon

AU - Lim, Chae Man

AU - Choi, Won Il

AU - Lee, Young Joo

AU - Kim, Seok Chan

AU - Chon, Gyu Rak

AU - Kim, Je Hyeong

AU - Kim, Jae Yeol

AU - Lim, Jaemin

AU - Rhee, Chin Kook

AU - Park, Sunghoon

AU - Kim, Ho Cheol

AU - Lee, Jin Hwa

AU - Lee, Ji Hyun

AU - Park, Jisook

AU - Cho, Juhee

AU - Koh, Shin Ok

AU - Suh, Gee Young

AU - Lim, So Yeon

AU - Hong, Sang Bum

AU - Huh, Jin Won

AU - Hong, Suk Kyung

AU - Choi, Won Il

AU - Park, Kwang Joo

AU - Park, Chan Kwon

AU - Kim, Ick Hee

AU - Kim, Ho Cheol

AU - Lee, Hyun

AU - Cho, Jae Hwa

PY - 2014/6

Y1 - 2014/6

N2 - Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.

AB - Introduction: This study evaluates the association between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and hospital mortality in general critically ill patients. Materials and Methods: This is a retrospective cohort study that analyzes prospective collected data from the Validation of Simplified acute physiology score 3 in Korean Intensive care unit study. The study population comprised patients who were consecutively admitted to participating intensive care units from July 1, 2010, to January 31, 2011. Univariate and multivariate logistic regression models were used to evaluate the effect of ECOG-PS on hospital mortality. Results: A total of 3868 patients were included in the analysis. There was a significant trend for increasing hospital mortality as the ECOG-PS grade became higher (. P < .001). There was a trend of increasing adjusted odds ratio for hospital mortality, with grade 1 of PS 1.4 (95% confidence intervals [CIs], 1.0-1.8), grade 2 of PS 2.0 (95% CIs, 1.5-2.7), grade 3 of PS 2.9 (95% CIs, 2.1-4.1), and grade 4 of PS 2.5 (95% CIs, 1.6-3.9). Also, there was a significant difference in all grades. Subgroup analysis showed a trend of increasing hospital mortality regardless of the presence of cancer. Conclusion: Preadmission PS, assessed with ECOG-PS in critically ill patients, has prognostic value in general critically ill patients.

KW - Hospital mortality

KW - Intensive care

KW - Performance status

KW - Prognosis

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U2 - 10.1016/j.jcrc.2014.01.016

DO - 10.1016/j.jcrc.2014.01.016

M3 - Article

C2 - 24603001

AN - SCOPUS:84899918556

SN - 0883-9441

VL - 29

SP - 409

EP - 413

JO - Journal of Critical Care

JF - Journal of Critical Care

IS - 3

ER -

Impact of Eastern Cooperative Oncology Group Performance Status on hospital mortality in critically ill patients

Abstract

Keywords

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