Imidazole-carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

Thanh Chung Pham, Dong Joon Lee, Do Hun Kim, Juyoung Yoon, Tran Dai Lam, Hwan Myung Kim, Songyi Lee

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A heavy-atom-free photosensitizer (CI) based on an imidazole-carbazole conjugate exhibited strong fluorescence emission and ROS generation via both type I and II mechanisms. In particular, CI showed efficient photodynamic therapy and fluorescence bioimaging under two-photon (TP) excitation (740 nm) toward HeLa cells with negligible dark toxicity.

Original languageEnglish
Pages (from-to)4503-4506
Number of pages4
JournalChemical Communications
Volume59
Issue number30
DOIs
StatePublished - 20 Mar 2023

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© 2023 The Royal Society of Chemistry.

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