Identification of tissue-specific expression of CXCL14 in black rockfish (Sebastes schlegelii)

Hyocheol Bae, Changwon Yang, Whasun Lim, Gwonhwa Song

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


CXCL14 is a chemokine which is orthologous in mammals and fish. CXCL14 has a functional role in different organs, with immunomodulatory functions in mammals, but its expression and function in fish is not well known. Moreover, it shows no effects related to immunity in the central nervous system or the reproductive tract in diverse species. Black rockfish (Sebastes schlegelii) is an economically important fish in Asian countries, whose CXCL14 expression pattern is yet to be understood. In this study, the homology of the CXCL14 amino acid sequence in S. schlegelii was compared with that in other species, including fish. Moreover, in situ hybridization analysis revealed that it was highly expressed in the brain and ovary of S. schlegelii. Taken together, we identified for the first time, the cell-specific expression of CXCL14 in S. schlegelii.

Original languageEnglish
Pages (from-to)135-142
Number of pages8
JournalFish and Shellfish Immunology
StatePublished - May 2021

Bibliographical note

Funding Information:
This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (MSIT), Republic of Korea [grant number: 2019R1A2C2089914 ].

Publisher Copyright:
© 2021 Elsevier Ltd


  • Black rockfish
  • Brain
  • CXCL14
  • Messenger RNA
  • Ovary


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