Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis

Young Suk Won; Hyo Jung Kwon; Goo Taeg Oh; Bang Hyun Kim; Chul Ho Lee; Yong Ho Park; Byung Hwa Hyun; Yang Kyu Choi

doi:10.1111/j.1348-0421.2002.tb02744.x

Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2^tm1Lau mice with dermatitis

Young Suk Won, Hyo Jung Kwon, Goo Taeg Oh, Bang Hyun Kim, Chul Ho Lee, Yong Ho Park, Byung Hwa Hyun, Yang Kyu Choi

Department of Life Science

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.

Original language	English
Pages (from-to)	629-632
Number of pages	4
Journal	Microbiology and Immunology
Volume	46
Issue number	9
DOIs	https://doi.org/10.1111/j.1348-0421.2002.tb02744.x
State	Published - 2002

Keywords

Granulomatous dermatitis
ITS-PCR
Staphylococcus xylosus

Access to Document

10.1111/j.1348-0421.2002.tb02744.x

Cite this

@article{f0040592e3de4385bc36245e88c7959d,

title = "Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis",

abstract = "Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.",

keywords = "Granulomatous dermatitis, ITS-PCR, Staphylococcus xylosus",

author = "Won, {Young Suk} and Kwon, {Hyo Jung} and Oh, {Goo Taeg} and Kim, {Bang Hyun} and Lee, {Chul Ho} and Park, {Yong Ho} and Hyun, {Byung Hwa} and Choi, {Yang Kyu}",

year = "2002",

doi = "10.1111/j.1348-0421.2002.tb02744.x",

language = "English",

volume = "46",

pages = "629--632",

journal = "Microbiology and Immunology",

issn = "0385-5600",

publisher = "Wiley-Blackwell",

number = "9",

}

TY - JOUR

T1 - Identification of Staphylococcus xylosus isolated from C57BL/6J-Nos2tm1Lau mice with dermatitis

AU - Won, Young Suk

AU - Kwon, Hyo Jung

AU - Oh, Goo Taeg

AU - Kim, Bang Hyun

AU - Lee, Chul Ho

AU - Park, Yong Ho

AU - Hyun, Byung Hwa

AU - Choi, Yang Kyu

PY - 2002

Y1 - 2002

N2 - Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.

AB - Coagulase negative staphylococci (CNS) are significant pathogens, particularly in medical device related infections and in immunocompromised patients. Five CNS strains were isolated from 5 NOS2 knock-out mice with dermatitis. Histologically, granulomatous dermatitis was found in the skin around the ear with epidermal ulceration. Dermal lesions included pustules, necrosis, and accumulations of neutrophils and macrophages. Isolates of the bacterial strains were identified to be Staphylococcus xylosus by the API STAPH kit and 16S-23S intergenic transcribed spacer-PCR. These results demonstrate the potential of this organism to be an opportunistic pathogen in immunocompromised mice.

KW - Granulomatous dermatitis

KW - ITS-PCR

KW - Staphylococcus xylosus

UR - http://www.scopus.com/inward/record.url?scp=0036378892&partnerID=8YFLogxK

U2 - 10.1111/j.1348-0421.2002.tb02744.x

DO - 10.1111/j.1348-0421.2002.tb02744.x

M3 - Article

C2 - 12437030

AN - SCOPUS:0036378892

SN - 0385-5600

VL - 46

SP - 629

EP - 632

JO - Microbiology and Immunology

JF - Microbiology and Immunology

IS - 9