Identification of signature genes associated with 5-fluorouracil-resistance in human gastric cancer cells

Saeyoung Park; Mina Lee; Hosoon Lee; Hae Yeong Kim; Yun Sil Lee; Shinwu Jeong; Doo Il Jeoung

doi:10.1023/A:1020665820180

Identification of signature genes associated with 5-fluorouracil-resistance in human gastric cancer cells

Saeyoung Park
, Mina Lee
, Hosoon Lee
, Hae Yeong Kim
, Yun Sil Lee
, Shinwu Jeong
, Doo Il Jeoung

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

A comparative cDNA microarray analysis was carried out using human gastric cancer cells and their derivative cells made resistant to 5-fluorouracil. Three genes, SRP72, DNA primase, and caspase-6, were identified that were transiently induced by 5-fluorouracil and also overexpressed in 5-fluorouracil-resistant gastric cancer cells.

Original language	English
Pages (from-to)	1651-1657
Number of pages	7
Journal	Biotechnology Letters
Volume	24
Issue number	20
DOIs	https://doi.org/10.1023/A:1020665820180
State	Published - Oct 2002

Keywords

5-fluorouracil
CDNA microarray
Gastric cancer cells
Signature genes

Access to Document

10.1023/A:1020665820180

Cite this

@article{97526363a97b4ecb8413d49bdc147201,

title = "Identification of signature genes associated with 5-fluorouracil-resistance in human gastric cancer cells",

abstract = "A comparative cDNA microarray analysis was carried out using human gastric cancer cells and their derivative cells made resistant to 5-fluorouracil. Three genes, SRP72, DNA primase, and caspase-6, were identified that were transiently induced by 5-fluorouracil and also overexpressed in 5-fluorouracil-resistant gastric cancer cells.",

keywords = "5-fluorouracil, CDNA microarray, Gastric cancer cells, Signature genes",

author = "Saeyoung Park and Mina Lee and Hosoon Lee and Kim, \{Hae Yeong\} and Lee, \{Yun Sil\} and Shinwu Jeong and Jeoung, \{Doo Il\}",

year = "2002",

month = oct,

doi = "10.1023/A:1020665820180",

language = "English",

volume = "24",

pages = "1651--1657",

journal = "Biotechnology Letters",

issn = "0141-5492",

publisher = "Springer Science and Business Media B.V.",

number = "20",

}

TY - JOUR

T1 - Identification of signature genes associated with 5-fluorouracil-resistance in human gastric cancer cells

AU - Park, Saeyoung

AU - Lee, Mina

AU - Lee, Hosoon

AU - Kim, Hae Yeong

AU - Lee, Yun Sil

AU - Jeong, Shinwu

AU - Jeoung, Doo Il

PY - 2002/10

Y1 - 2002/10

N2 - A comparative cDNA microarray analysis was carried out using human gastric cancer cells and their derivative cells made resistant to 5-fluorouracil. Three genes, SRP72, DNA primase, and caspase-6, were identified that were transiently induced by 5-fluorouracil and also overexpressed in 5-fluorouracil-resistant gastric cancer cells.

AB - A comparative cDNA microarray analysis was carried out using human gastric cancer cells and their derivative cells made resistant to 5-fluorouracil. Three genes, SRP72, DNA primase, and caspase-6, were identified that were transiently induced by 5-fluorouracil and also overexpressed in 5-fluorouracil-resistant gastric cancer cells.

KW - 5-fluorouracil

KW - CDNA microarray

KW - Gastric cancer cells

KW - Signature genes

UR - https://www.scopus.com/pages/publications/0036804103

U2 - 10.1023/A:1020665820180

DO - 10.1023/A:1020665820180

M3 - Article

AN - SCOPUS:0036804103

SN - 0141-5492

VL - 24

SP - 1651

EP - 1657

JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 20

ER -

Identification of signature genes associated with 5-fluorouracil-resistance in human gastric cancer cells

Abstract

Keywords

Access to Document

Fingerprint

Cite this