Identification of a new cytotoxic biflavanone from Selaginella doederleinii

Na Youn Lee, Hye Young Min, Jun Lee, Joo Won Nam, Yoo Jin Lee, Ah Reum Han, Adam Wiryawan, Wahyu Suprapto, Sang Kook Lee, Eun Kyoung Sec

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

A new biflavanone, 2,2″,3,3″-tetrahydrorobustaflavone 7,4′,7″ trimethyl ether (1) was isolated from the whole plant of Selaginella doederleinii HIERON. (Selaginellaceae) together with the known biflavonoid, robustaflavone 7,4′,7″ trimethyl ether (2) as the cytotoxic constituents against the three human cancer cell lines, HCT, NCI-H358, and K562. The structure of the new compound 1 was elucidated by spectral analysis including various 1D-and 2D NMR experiments.

Original languageEnglish
Pages (from-to)1360-1361
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume56
Issue number9
DOIs
StatePublished - Sep 2008

Keywords

  • Biflavanone
  • Cytotoxicity
  • Selaginella doederleinii
  • Selaginellaceae

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