Hypocholesterolemic activity of hesperetin derivatives

Tae Sook Jeong; Eun Eai Kim; Chul Ho Lee; Jung Hoon Oh; Surk Sik Moon; Woo Song Lee; Goo Taeg Oh; Sangku Lee; Song Hae Bok

doi:10.1016/S0960-894X(03)00574-2

Hypocholesterolemic activity of hesperetin derivatives

Tae Sook Jeong
, Eun Eai Kim
, Chul Ho Lee
, Jung Hoon Oh
, Surk Sik Moon
, Woo Song Lee
, Goo Taeg Oh
, Sangku Lee
, Song Hae Bok

Department of Life Science

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

Original language	English
Pages (from-to)	2663-2665
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	13
Issue number	16
DOIs	https://doi.org/10.1016/S0960-894X(03)00574-2
State	Published - 18 Aug 2003

Bibliographical note

Funding Information:
This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.

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title = "Hypocholesterolemic activity of hesperetin derivatives",

abstract = "Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.",

author = "Jeong, \{Tae Sook\} and Kim, \{Eun Eai\} and Lee, \{Chul Ho\} and Oh, \{Jung Hoon\} and Moon, \{Surk Sik\} and Lee, \{Woo Song\} and Oh, \{Goo Taeg\} and Sangku Lee and Bok, \{Song Hae\}",

note = "Funding Information: This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.",

year = "2003",

month = aug,

day = "18",

doi = "10.1016/S0960-894X(03)00574-2",

language = "English",

volume = "13",

pages = "2663--2665",

journal = "Bioorganic and Medicinal Chemistry Letters",

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TY - JOUR

T1 - Hypocholesterolemic activity of hesperetin derivatives

AU - Jeong, Tae Sook

AU - Kim, Eun Eai

AU - Lee, Chul Ho

AU - Oh, Jung Hoon

AU - Moon, Surk Sik

AU - Lee, Woo Song

AU - Oh, Goo Taeg

AU - Lee, Sangku

AU - Bok, Song Hae

N1 - Funding Information: This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.

PY - 2003/8/18

Y1 - 2003/8/18

N2 - Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

AB - Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

UR - https://www.scopus.com/pages/publications/0038149076

U2 - 10.1016/S0960-894X(03)00574-2

DO - 10.1016/S0960-894X(03)00574-2

M3 - Article

C2 - 12873489

AN - SCOPUS:0038149076

SN - 0960-894X

VL - 13

SP - 2663

EP - 2665

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 16

ER -

Hypocholesterolemic activity of hesperetin derivatives

Abstract

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