Hypocholesterolemic activity of hesperetin derivatives

Tae Sook Jeong, Eun Eai Kim, Chul Ho Lee, Jung Hoon Oh, Surk Sik Moon, Woo Song Lee, Goo Taeg Oh, Sangku Lee, Song Hae Bok

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

Original languageEnglish
Pages (from-to)2663-2665
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Issue number16
StatePublished - 18 Aug 2003

Bibliographical note

Funding Information:
This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.


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