Hypocholesterolemic activity of hesperetin derivatives

Tae Sook Jeong; Eun Eai Kim; Chul Ho Lee; Jung Hoon Oh; Surk Sik Moon; Woo Song Lee; Goo Taeg Oh; Sangku Lee; Song Hae Bok

doi:10.1016/S0960-894X(03)00574-2

Hypocholesterolemic activity of hesperetin derivatives

Tae Sook Jeong, Eun Eai Kim, Chul Ho Lee, Jung Hoon Oh, Surk Sik Moon, Woo Song Lee, Goo Taeg Oh, Sangku Lee, Song Hae Bok

Department of Life Science

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

Original language	English
Pages (from-to)	2663-2665
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	13
Issue number	16
DOIs	https://doi.org/10.1016/S0960-894X(03)00574-2
State	Published - 18 Aug 2003

Bibliographical note

Funding Information:
This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.

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title = "Hypocholesterolemic activity of hesperetin derivatives",

abstract = "Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.",

author = "Jeong, {Tae Sook} and Kim, {Eun Eai} and Lee, {Chul Ho} and Oh, {Jung Hoon} and Moon, {Surk Sik} and Lee, {Woo Song} and Oh, {Goo Taeg} and Sangku Lee and Bok, {Song Hae}",

note = "Funding Information: This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.",

year = "2003",

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day = "18",

doi = "10.1016/S0960-894X(03)00574-2",

language = "English",

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journal = "Bioorganic and Medicinal Chemistry Letters",

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TY - JOUR

T1 - Hypocholesterolemic activity of hesperetin derivatives

AU - Jeong, Tae Sook

AU - Kim, Eun Eai

AU - Lee, Chul Ho

AU - Oh, Jung Hoon

AU - Moon, Surk Sik

AU - Lee, Woo Song

AU - Oh, Goo Taeg

AU - Lee, Sangku

AU - Bok, Song Hae

N1 - Funding Information: This work was supported by grants from the Ministry of Science and Technology (M1-0015-00-0012), Korea.

PY - 2003/8/18

Y1 - 2003/8/18

N2 - Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

AB - Hesperetin ester and ether derivatives possessing a long alkyl chain were synthesized for examining their hypocholesterolemic activities in high cholesterol-fed mice. Hesperetin 7-O-lauryl ether (4b) and hesperetin 7-O-oleyl ether (4e) exhibited strong cholesterol-lowering effects.

UR - http://www.scopus.com/inward/record.url?scp=0038149076&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(03)00574-2

DO - 10.1016/S0960-894X(03)00574-2

M3 - Article

C2 - 12873489

AN - SCOPUS:0038149076

SN - 0960-894X

VL - 13

SP - 2663

EP - 2665

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 16

ER -

Hypocholesterolemic activity of hesperetin derivatives

Abstract

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