Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates

Kei Ohkubo; Yoshihiko Moro-Oka; Shunichi Fukuzumi

doi:10.1039/b600111d

Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates

Kei Ohkubo, Yoshihiko Moro-Oka, Shunichi Fukuzumi

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.

Original language	English
Pages (from-to)	999-1001
Number of pages	3
Journal	Organic and Biomolecular Chemistry
Volume	4
Issue number	6
DOIs	https://doi.org/10.1039/b600111d
State	Published - 2006

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title = "Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates",

abstract = "The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.",

author = "Kei Ohkubo and Yoshihiko Moro-Oka and Shunichi Fukuzumi",

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doi = "10.1039/b600111d",

language = "English",

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journal = "Organic and Biomolecular Chemistry",

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T1 - Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates

AU - Ohkubo, Kei

AU - Moro-Oka, Yoshihiko

AU - Fukuzumi, Shunichi

PY - 2006

Y1 - 2006

N2 - The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.

AB - The reactivity of neurotransmitters toward hydrogen abstraction by an active oxygen species (the cumylperoxyl radical) is comparable to that of a strong antioxidant such as catechin due to the strong intramolecular hydrogen bonding, which has been successfully detected by ESR.

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U2 - 10.1039/b600111d

DO - 10.1039/b600111d

M3 - Article

C2 - 16525542

AN - SCOPUS:33644894217

SN - 1477-0520

VL - 4

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EP - 1001

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 6

ER -

Hydrogen abstraction from neurotransmitters by active oxygen species facilitated by intramolecular hydrogen bonding in the radical intermediates

Abstract

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