HLA allele distribution associated with adverse drug reactions in organ transplant patients

Kye Hwa Lee, Yi Jun Kim, Hyo Jung Kim, Ju Han Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The results of Human Leukocyte Antigen (HLA) antigen testing in transplant patients are not generally used to predict future adverse events. In this study, free-text HLA screening results of transplant patients were analyzed and stored in a database, and the frequencies of patients with adverse events according to HLA allele were extracted. Approximately 25% of patients had HLA alleles associated with serious drug side effects.

Original languageEnglish
Title of host publicationMEDINFO 2019
Subtitle of host publicationHealth and Wellbeing e-Networks for All - Proceedings of the 17th World Congress on Medical and Health Informatics
EditorsBrigitte Seroussi, Lucila Ohno-Machado, Lucila Ohno-Machado, Brigitte Seroussi
PublisherIOS Press
Pages1851-1852
Number of pages2
ISBN (Electronic)9781643680026
DOIs
StatePublished - 21 Aug 2019
Event17th World Congress on Medical and Health Informatics, MEDINFO 2019 - Lyon, France
Duration: 25 Aug 201930 Aug 2019

Publication series

NameStudies in Health Technology and Informatics
Volume264
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference17th World Congress on Medical and Health Informatics, MEDINFO 2019
Country/TerritoryFrance
CityLyon
Period25/08/1930/08/19

Keywords

  • Adverse Reactions
  • Drug-Related Side Effects
  • HLA Antigens
  • Pharmacogenomic Testing

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