Background: The relationship between anaphylaxis and tumor metastasis remains unknown at the molecular level.Results: The miR-384/HDAC3 axis regulates an interaction between tumor cells and mast cells. Conclusion: HDAC3 mediates a positive feedback loop between anaphylaxis and tumor metastasis. Significance: HDAC3 can be a target for the development of allergy and cancer therapeutics.
|Number of pages||19|
|Journal||Journal of Biological Chemistry|
|State||Published - 25 Apr 2014|