TY - GEN
T1 - Highly-accurate, implantable micromanipulator for single neuron recordings
AU - Yang, Sungwook
AU - Lee, Semin
AU - Park, Kitae
AU - Kim, Jinseok
AU - Cho, Jeiwon
AU - Shin, Hee Sup
AU - Yoon, Eui Sung
PY - 2010
Y1 - 2010
N2 - A precise and implantable micromanipulator is presented for automatically advancing electrodes during single unit recordings in freely-behaving animals. The modular design and enhanced clamping mechanism with simple mechanical components are designed to provide reliable linear motion using a piezo motor with a stroke of 3 mm. To be specific, a closed loop control system, based on the position feedback from a magnetoresistive (MR) sensor, was implemented to overcome the non-linear characteristics of the piezo motor and to locate electrodes precisely at the targeted position with the accuracy of 1 μm, even under load. The weight of the micromanipulator is only 0.84 g when it is fully assembled with the MR sensor, PCBs, and connectors. In addition, a protective cover is employed to prevent breakage during semi-chronic recording. The positioning performance of the micromanipulator was tested at various loading conditions using various control methods. Finally, the activities of a single unit were isolated successfully using small step adjustments, such as 1 to 5 μm, in freely-moving mice.
AB - A precise and implantable micromanipulator is presented for automatically advancing electrodes during single unit recordings in freely-behaving animals. The modular design and enhanced clamping mechanism with simple mechanical components are designed to provide reliable linear motion using a piezo motor with a stroke of 3 mm. To be specific, a closed loop control system, based on the position feedback from a magnetoresistive (MR) sensor, was implemented to overcome the non-linear characteristics of the piezo motor and to locate electrodes precisely at the targeted position with the accuracy of 1 μm, even under load. The weight of the micromanipulator is only 0.84 g when it is fully assembled with the MR sensor, PCBs, and connectors. In addition, a protective cover is employed to prevent breakage during semi-chronic recording. The positioning performance of the micromanipulator was tested at various loading conditions using various control methods. Finally, the activities of a single unit were isolated successfully using small step adjustments, such as 1 to 5 μm, in freely-moving mice.
UR - http://www.scopus.com/inward/record.url?scp=77955814267&partnerID=8YFLogxK
U2 - 10.1109/ROBOT.2010.5509360
DO - 10.1109/ROBOT.2010.5509360
M3 - Conference contribution
AN - SCOPUS:77955814267
SN - 9781424450381
T3 - Proceedings - IEEE International Conference on Robotics and Automation
SP - 5070
EP - 5075
BT - 2010 IEEE International Conference on Robotics and Automation, ICRA 2010
T2 - 2010 IEEE International Conference on Robotics and Automation, ICRA 2010
Y2 - 3 May 2010 through 7 May 2010
ER -