High sleep reactivity in shift workers is associated with increased sleep disturbance, mood problems, and reduced quality of life

Introduction: Shift work disrupts circadian rhythms, causing sleep and mood problems. Sleep reactivity—the sensitivity of sleep to stress—may affect how shift workers cope with these disruptions. This study investigated the relationship between sleep reactivity and shift work, exploring associations between sleep reactivity and sleep disturbance, mood symptoms, and quality of life in shift workers. Methods: In a cross-sectional design, 132 participants (79 shift workers and 53 controls) were assessed using the Ford Insomnia Response to Stress Test (FIRST), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and World Health Organization Quality of Life (WHOQOL). We compared the self-reported measurements between shift workers and controls. Two-way ANOVA was performed to explore the interaction effects between shift work and sleep reactivity on sleep, mood parameters, and quality of life. Multiple linear regression analysis was conducted to identify factors associated with sleep, mood, and quality of life among shift workers. Results: Shift workers scored higher on ISI and BDI compared to controls. Two-way ANOVA revealed an interaction effect between shift work and sleep reactivity on WHOQOL. Regression analysis indicated that high sleep reactivity was associated with higher ISI, BDI, BAI, and lower WHOQOL among shift workers. Conclusion: Sleep reactivity significantly affected shift worker's quality of life. Our findings indicate that high sleep reactivity in shift workers was associated with increased sleep disturbance, mood problems, and decreased quality of life, implying that sleep reactivity may predict shift work tolerance.