Hepatectomy vs radiofrequency ablation for colorectal liver metastasis: A propensity score analysis

Huisong Lee, Jin Seok Heo, Yong Beom Cho, Seong Hyeon Yun, Hee Cheol Kim, Woo Yong Lee, Seong Ho Choi, Dong Wook Choi

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

AIM: To compare outcomes from radiofrequency ablation (RFA) and hepatectomy for treatment of colorectal liver metastasis (CRLM). METHODS: From January 2000 to December 2009, 408 patients underwent curative intent treatment for CRLM. We excluded patients using the criteria: size of CRLM > 3 cm, number of CRLM ≥ 5, percutaneous RFA, follow-up period < 12 mo, double primary cancer, or treatment with both RFA and hepatectomy. We matched 51 patients who underwent RFA with 102 patients who underwent hepatectomy by propensity scores. RESULTS: The median follow-up period was 45 mo (range, 12 mo to 158 mo). Hepatic recurrence was more frequent in the RFA than the hepatectomy group (P = 0.021) although extrahepatic recurrence curves were similar (P = 0.716). Survival curves of hepatectomy group were better than that of RFA for multiple, large (> 2 cm) CRLM (P = 0.034). However, survival curves were similar for single or small (≤ 2 cm) CRLM (P = 0.714, P = 0.740). CONCLUSION: Hepatectomy is better than RFA for the treatment of CRLM. However, RFA might be suitable for selected patients with single, small (≤ 2 cm) CRLM.

Original languageEnglish
Pages (from-to)3300-3307
Number of pages8
JournalWorld Journal of Gastroenterology
Volume21
Issue number11
DOIs
StatePublished - 21 Mar 2015

Keywords

  • Catheter ablation
  • Colorectal neoplasm
  • Hepatectomy
  • Liver
  • Metastasis

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