Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

Jin Hyun Chung; Hye Ryun Lim; Tek Hyung Lee; Mi Hee Lee; Yeon I. Woo; Hyun Sook Baek; Seung Jin Lee; Jeong Koo Kim; Jong Chul Park

doi:10.4028/0-87849-436-7.93

Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

Jin Hyun Chung, Hye Ryun Lim, Tek Hyung Lee, Mi Hee Lee, Yeon I. Woo, Hyun Sook Baek, Seung Jin Lee, Jeong Koo Kim, Jong Chul Park

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

Original language	English
Pages (from-to)	93-96
Number of pages	4
Journal	Key Engineering Materials
Volume	342-343
DOIs	https://doi.org/10.4028/0-87849-436-7.93
State	Published - 2007

Keywords

Cell proliferation
Epigallocatechin 3-0-gallate
Human umbilical vein endothelial cell
Poly (D,L-latic-co-glycolic acid)
Smooth muscle cell

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title = "Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG",

abstract = "Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.",

keywords = "Cell proliferation, Epigallocatechin 3-0-gallate, Human umbilical vein endothelial cell, Poly (D,L-latic-co-glycolic acid), Smooth muscle cell",

author = "Chung, {Jin Hyun} and Lim, {Hye Ryun} and Lee, {Tek Hyung} and Lee, {Mi Hee} and Woo, {Yeon I.} and Baek, {Hyun Sook} and Lee, {Seung Jin} and Kim, {Jeong Koo} and Park, {Jong Chul}",

year = "2007",

doi = "10.4028/0-87849-436-7.93",

language = "English",

volume = "342-343",

pages = "93--96",

journal = "Key Engineering Materials",

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T1 - Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

AU - Chung, Jin Hyun

AU - Lim, Hye Ryun

AU - Lee, Tek Hyung

AU - Lee, Mi Hee

AU - Woo, Yeon I.

AU - Baek, Hyun Sook

AU - Lee, Seung Jin

AU - Kim, Jeong Koo

AU - Park, Jong Chul

PY - 2007

Y1 - 2007

N2 - Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

AB - Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

KW - Cell proliferation

KW - Epigallocatechin 3-0-gallate

KW - Human umbilical vein endothelial cell

KW - Poly (D,L-latic-co-glycolic acid)

KW - Smooth muscle cell

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U2 - 10.4028/0-87849-436-7.93

DO - 10.4028/0-87849-436-7.93

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VL - 342-343

SP - 93

EP - 96

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

Abstract

Keywords

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