Genetic landscape of open chromatin in yeast

Kibaick Lee, Sang Cheol Kim, Inkyung Jung, Kwoneel Kim, Jungmin Seo, Heun Sik Lee, Gireesh K. Bogu, Dongsup Kim, Sanghyuk Lee, Byungwook Lee, Jung Kyoon Choi

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The genetic basis of gene expression has been studied in various organisms [1]-[5]. For example, two different strains of Saccharomyces cerevisiae (BY and RM) were crossed to produce a number of different genetic recombinants, and their expression levels and genotypes were analyzed [1], [6]. We previously utilized this system to separate the cis-and transcomponents of variation in gene expression [7]. Tirosh et al. [8] profiled nucleosome patterns in the inter-specific hybrids of two yeast species to dissect cis-and trans-effects on nucleosome positioning. Recently, variations in the binding patterns of transcription factors (TFs) have begun to be studied [9]-[11].

Original languageEnglish
Title of host publicationInvestigations in Yeast Functional Genomics and Molecular Biology
PublisherApple Academic Press
Number of pages19
ISBN (Electronic)9781482240962
ISBN (Print)9781771880107
StatePublished - 1 Jan 2014

Bibliographical note

Publisher Copyright:
© 2014 by Apple Academic Press, Inc.


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