Galactography acquired with digital mammography in patients with nipple discharge: A retrospective analysis

Sung Hun Kim, Eun Suk Cha, Hyeon Sook Kim, Bong Joo Kang, Jae Jung Choi, Ji Han Jung

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Purpose: To evaluate the galactographic findings taken with digital mammography and to compare the findings between benign and malignant breast diseases. Materials and methods: Galactographic findings were retrospectively analyzed and compared with histopathological results for 42 patients who showed abnormal findings on galactography and had histologically proven diagnoses between January 2005 and March 2008. A galactography was acquired using full-field digital mammography (Hologic Lorad Selenia; Danbury, USA). The difference in galactographic findings between malignant and benign breast diseases was analyzed using χ2 test. A value of P < 0.05 was considered statistically significant. Results: Of the total 42 cases, 11 cases were malignant breast diseases and 31 were benign diseases. Common galactographic findings of benign diseases include ductal obstruction (48.3%) and single filling defect (51.6%), and common findings for malignant tumor include ductal dilatation (72.7%) and stenosis (63.6%). Ductal stenosis, microcalcifications or mass adjacent to abnormal duct, multiple filling defects, ductal wall irregularity, ductal distortion and irregular filling defects were more prevalently seen in malignant cases. A single filling defect and lobular filling defect was more prevalently seen in benign cases (P < 0.05). Ductal dilatation was a common finding in both malignant and benign cases with no significant difference. Conclusions: Ductal lesions were well visualized on galactography acquired with a digital mammography. A preoperative diagnostic galactography is useful in making a differential diagnosis between benign diseases and malignant tumors in patients with pathologic nipple discharge.

Original languageEnglish
Pages (from-to)217-222
Number of pages6
JournalArchives of Gynecology and Obstetrics
Volume280
Issue number2
DOIs
StatePublished - Aug 2009

Keywords

  • Breast
  • Breast neoplasms
  • Diagnosis
  • Duct
  • Galactography

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