Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance

Kyungwon Lee; Ki Hyung Park; Seok Hoon Jeong; Hwan Sub Lim; Jong Hee Shin; Dongeun Yong; Gyoung Yim Ha; Yunsop Chong; Jae Seok Kim; Sunjoo Kim; Namhee Ryoo; Mun Yeun Kim; Chulhun L. Chang; Mi Na Kim; Wee Gyo Lee; Myungshin Kim; Chea Hoon Lee; Jeong Ho Kim; Joseph Jeong; Ji Hyun Cho; Young Uh; Ki Sook Hong; Bo Moon Shin; Hye Soo Lee; Sook Jin Jang; Ae Ja Park; Young Joo Cha; Young Jin Choi; Sung Ha Kang; Chang Hyun Rhim; Myung Hee Lee; Wonkeun Song; Tae Yeal Choi; Eui Chong Kim; Jung Oak Kang; Yeon Joon Park; Seong Geun Hong; Ah Kim Young; Hee Joo Lee; Jongwook Lee; Young Joon Lee; Miae Lee; Hee Bong Shin; Young Ree Kim; Seung Ok Lee; Sung Hee Lee

doi:10.3349/ymj.2006.47.1.43

Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance

Kyungwon Lee, Ki Hyung Park, Seok Hoon Jeong, Hwan Sub Lim, Jong Hee Shin, Dongeun Yong, Gyoung Yim Ha, Yunsop Chong, Jae Seok Kim, Sunjoo Kim, Namhee Ryoo, Mun Yeun Kim, Chulhun L. Chang, Mi Na Kim, Wee Gyo Lee, Myungshin Kim, Chea Hoon Lee, Jeong Ho Kim, Joseph Jeong, Ji Hyun ChoYoung Uh, Ki Sook Hong, Bo Moon Shin, Hye Soo Lee, Sook Jin Jang, Ae Ja Park, Young Joo Cha, Young Jin Choi, Sung Ha Kang, Chang Hyun Rhim, Myung Hee Lee, Wonkeun Song, Tae Yeal Choi, Eui Chong Kim, Jung Oak Kang, Yeon Joon Park, Seong Geun Hong, Ah Kim Young, Hee Joo Lee, Jongwook Lee, Young Joon Lee, Miae Lee, Hee Bong Shin, Young Ree Kim, Seung Ok Lee, Sung Hee Lee

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%). expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases, in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%): were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E coli.

Original language	English
Pages (from-to)	43-54
Number of pages	12
Journal	Yonsei Medical Journal
Volume	47
Issue number	1
DOIs	https://doi.org/10.3349/ymj.2006.47.1.43
State	Published - 6 Feb 2006

Keywords

Antimicrobial resistance surveillance
Fluoroquinolone resistance
Imipenem
Korea
Vancomycin resistance

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10.3349/ymj.2006.47.1.43

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Lee, K., Park, K. H., Jeong, S. H., Lim, H. S., Shin, J. H., Yong, D., Ha, G. Y., Chong, Y., Kim, J. S., Kim, S., Ryoo, N., Kim, M. Y., Chang, C. L., Kim, M. N., Lee, W. G., Kim, M., Lee, C. H., Kim, J. H., Jeong, J., ... Lee, S. H. (2006). Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance. Yonsei Medical Journal, 47(1), 43-54. https://doi.org/10.3349/ymj.2006.47.1.43

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title = "Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance",

abstract = "Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%). expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases, in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%): were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E coli.",

keywords = "Antimicrobial resistance surveillance, Fluoroquinolone resistance, Imipenem, Korea, Vancomycin resistance",

author = "Kyungwon Lee and Park, {Ki Hyung} and Jeong, {Seok Hoon} and Lim, {Hwan Sub} and Shin, {Jong Hee} and Dongeun Yong and Ha, {Gyoung Yim} and Yunsop Chong and Kim, {Jae Seok} and Sunjoo Kim and Namhee Ryoo and Kim, {Mun Yeun} and Chang, {Chulhun L.} and Kim, {Mi Na} and Lee, {Wee Gyo} and Myungshin Kim and Lee, {Chea Hoon} and Kim, {Jeong Ho} and Joseph Jeong and Cho, {Ji Hyun} and Young Uh and Hong, {Ki Sook} and Shin, {Bo Moon} and Lee, {Hye Soo} and Jang, {Sook Jin} and Park, {Ae Ja} and Cha, {Young Joo} and Choi, {Young Jin} and Kang, {Sung Ha} and Rhim, {Chang Hyun} and Lee, {Myung Hee} and Wonkeun Song and Choi, {Tae Yeal} and Kim, {Eui Chong} and Kang, {Jung Oak} and Park, {Yeon Joon} and Hong, {Seong Geun} and Young, {Ah Kim} and Lee, {Hee Joo} and Jongwook Lee and Lee, {Young Joon} and Miae Lee and Shin, {Hee Bong} and Kim, {Young Ree} and Lee, {Seung Ok} and Lee, {Sung Hee}",

year = "2006",

month = feb,

day = "6",

doi = "10.3349/ymj.2006.47.1.43",

language = "English",

volume = "47",

pages = "43--54",

journal = "Yonsei Medical Journal",

issn = "0513-5796",

publisher = "Yonsei University College of Medicine",

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Lee, K, Park, KH, Jeong, SH, Lim, HS, Shin, JH, Yong, D, Ha, GY, Chong, Y, Kim, JS, Kim, S, Ryoo, N, Kim, MY, Chang, CL, Kim, MN, Lee, WG, Kim, M, Lee, CH, Kim, JH, Jeong, J, Cho, JH, Uh, Y, Hong, KS, Shin, BM, Lee, HS, Jang, SJ, Park, AJ, Cha, YJ, Choi, YJ, Kang, SH, Rhim, CH, Lee, MH, Song, W, Choi, TY, Kim, EC, Kang, JO, Park, YJ, Hong, SG, Young, AK, Lee, HJ, Lee, J, Lee, YJ, Lee, M, Shin, HB, Kim, YR, Lee, SO & Lee, SH 2006, 'Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance', Yonsei Medical Journal, vol. 47, no. 1, pp. 43-54. https://doi.org/10.3349/ymj.2006.47.1.43

Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance. / Lee, Kyungwon; Park, Ki Hyung; Jeong, Seok Hoon et al.
In: Yonsei Medical Journal, Vol. 47, No. 1, 06.02.2006, p. 43-54.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea

T2 - 2003 KONSAR surveillance

AU - Lee, Kyungwon

AU - Park, Ki Hyung

AU - Jeong, Seok Hoon

AU - Lim, Hwan Sub

AU - Shin, Jong Hee

AU - Yong, Dongeun

AU - Ha, Gyoung Yim

AU - Chong, Yunsop

AU - Kim, Jae Seok

AU - Kim, Sunjoo

AU - Ryoo, Namhee

AU - Kim, Mun Yeun

AU - Chang, Chulhun L.

AU - Kim, Mi Na

AU - Lee, Wee Gyo

AU - Kim, Myungshin

AU - Lee, Chea Hoon

AU - Kim, Jeong Ho

AU - Jeong, Joseph

AU - Cho, Ji Hyun

AU - Uh, Young

AU - Hong, Ki Sook

AU - Shin, Bo Moon

AU - Lee, Hye Soo

AU - Jang, Sook Jin

AU - Park, Ae Ja

AU - Cha, Young Joo

AU - Choi, Young Jin

AU - Kang, Sung Ha

AU - Rhim, Chang Hyun

AU - Lee, Myung Hee

AU - Song, Wonkeun

AU - Choi, Tae Yeal

AU - Kim, Eui Chong

AU - Kang, Jung Oak

AU - Park, Yeon Joon

AU - Hong, Seong Geun

AU - Young, Ah Kim

AU - Lee, Hee Joo

AU - Lee, Jongwook

AU - Lee, Young Joon

AU - Lee, Miae

AU - Shin, Hee Bong

AU - Kim, Young Ree

AU - Lee, Seung Ok

AU - Lee, Sung Hee

PY - 2006/2/6

Y1 - 2006/2/6

N2 - Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%). expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases, in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%): were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E coli.

AB - Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%). expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases, in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%): were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E coli.

KW - Antimicrobial resistance surveillance

KW - Fluoroquinolone resistance

KW - Imipenem

KW - Korea

KW - Vancomycin resistance

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AN - SCOPUS:33644811340

SN - 0513-5796

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JO - Yonsei Medical Journal

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ER -

Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance

Abstract

Keywords

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