Functionalized Fe 3O 4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity

Gyusik Kang; Hyunjong Son; Jung Mi Lim; Hee Seek Kweon; In Soo Lee; Dongmin Kang; Jong Hwa Jung

doi:10.1002/chem.201200294

Functionalized Fe ₃O ₄ nanoparticles for detecting zinc ions in living cells and their cytotoxicity

Gyusik Kang
, Hyunjong Son
, Jung Mi Lim
, Hee Seek Kweon
, In Soo Lee
, Dongmin Kang
, Jong Hwa Jung

Department of Life Science

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe ₃O ₄ nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn ²⁺ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn ²⁺ levels in living cells (see figure).

Original language	English
Pages (from-to)	5843-5847
Number of pages	5
Journal	Chemistry - A European Journal
Volume	18
Issue number	19
DOIs	https://doi.org/10.1002/chem.201200294
State	Published - 7 May 2012

Keywords

biosensors
chromophores
fluorophores
nanoparticles
zinc

Access to Document

10.1002/chem.201200294

Cite this

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title = "Functionalized Fe 3O 4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity",

abstract = "The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O 4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn 2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn 2+ levels in living cells (see figure).",

keywords = "biosensors, chromophores, fluorophores, nanoparticles, zinc",

author = "Gyusik Kang and Hyunjong Son and Lim, \{Jung Mi\} and Kweon, \{Hee Seek\} and Lee, \{In Soo\} and Dongmin Kang and Jung, \{Jong Hwa\}",

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AU - Kang, Gyusik

AU - Son, Hyunjong

AU - Lim, Jung Mi

AU - Kweon, Hee Seek

AU - Lee, In Soo

AU - Kang, Dongmin

AU - Jung, Jong Hwa

PY - 2012/5/7

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N2 - The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O 4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn 2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn 2+ levels in living cells (see figure).

AB - The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O 4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn 2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn 2+ levels in living cells (see figure).

KW - biosensors

KW - chromophores

KW - fluorophores

KW - nanoparticles

KW - zinc

UR - https://www.scopus.com/pages/publications/84860743141

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DO - 10.1002/chem.201200294

M3 - Article

C2 - 22517629

AN - SCOPUS:84860743141

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