Functionalized Fe 3O 4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity

Gyusik Kang; Hyunjong Son; Jung Mi Lim; Hee Seek Kweon; In Soo Lee; Dongmin Kang; Jong Hwa Jung

doi:10.1002/chem.201200294

Functionalized Fe ₃O ₄ nanoparticles for detecting zinc ions in living cells and their cytotoxicity

Gyusik Kang, Hyunjong Son, Jung Mi Lim, Hee Seek Kweon, In Soo Lee, Dongmin Kang, Jong Hwa Jung

Department of Life Science

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe ₃O ₄ nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn ²⁺ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn ²⁺ levels in living cells (see figure).

Original language	English
Pages (from-to)	5843-5847
Number of pages	5
Journal	Chemistry - A European Journal
Volume	18
Issue number	19
DOIs	https://doi.org/10.1002/chem.201200294
State	Published - 7 May 2012

Keywords

biosensors
chromophores
fluorophores
nanoparticles
zinc

Access to Document

10.1002/chem.201200294

Cite this

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abstract = "The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe 3O 4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn 2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn 2+ levels in living cells (see figure).",

keywords = "biosensors, chromophores, fluorophores, nanoparticles, zinc",

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AU - Lee, In Soo

AU - Kang, Dongmin

AU - Jung, Jong Hwa

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KW - biosensors

KW - chromophores

KW - fluorophores

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KW - zinc

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