TY - JOUR
T1 - Free breathing three-dimensional late gadolinium enhancement cardiovascular magnetic resonance using outer volume suppressed projection navigators
AU - Menon, Rajiv G.
AU - Miller, G. Wilson
AU - Jeudy, Jean
AU - Rajagopalan, Sanjay
AU - Shin, Taehoon
N1 - Funding Information:
The project described was supported in part by NIH R21 EB019206. The authors thank Dr Anuj Gupta (MD, University of Maryland, Baltimore, MD) for assistance with recruiting patients. The authors acknowledge the technicians at the University of Maryland Medical Center for performing the clinical CMR examinations.
Publisher Copyright:
© 2016 International Society for Magnetic Resonance in Medicine
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Purpose: To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). Methods: The proposed 3D FB-LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one-dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB-LGE and 2D BH-LGE scans were performed on 29 cardiac patients. Qualitative analysis and quantitative analysis (in patients with scar) were performed. Results: No significant differences were noted between the 3D FB-LGE and 2D BH-LGE data sets in terms of overall image quality score (2D: 4.69 ± 0.60 versus 3D: 4.55 ± 0.51, P = 0.46) and image artifact score (2D: 1.10 ± 0.31 versus 3D: 1.17 ± 0.38; P = 0.63). The average difference in fractional scar volume between the 3D and 2D methods was 1.9% (n = 5). Acquisition time was significantly shorter for the 3D FB-LGE over 2D BH-LGE by a factor of 2.83 ± 0.77 (P < 0.0001). Conclusions: The 3D FB-LGE is a viable option for patients, particularly in acute settings or in patients who are unable to comply with breath-hold instructions. Magn Reson Med 77:1533–1543, 2017.
AB - Purpose: To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). Methods: The proposed 3D FB-LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one-dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB-LGE and 2D BH-LGE scans were performed on 29 cardiac patients. Qualitative analysis and quantitative analysis (in patients with scar) were performed. Results: No significant differences were noted between the 3D FB-LGE and 2D BH-LGE data sets in terms of overall image quality score (2D: 4.69 ± 0.60 versus 3D: 4.55 ± 0.51, P = 0.46) and image artifact score (2D: 1.10 ± 0.31 versus 3D: 1.17 ± 0.38; P = 0.63). The average difference in fractional scar volume between the 3D and 2D methods was 1.9% (n = 5). Acquisition time was significantly shorter for the 3D FB-LGE over 2D BH-LGE by a factor of 2.83 ± 0.77 (P < 0.0001). Conclusions: The 3D FB-LGE is a viable option for patients, particularly in acute settings or in patients who are unable to comply with breath-hold instructions. Magn Reson Med 77:1533–1543, 2017.
KW - 3D late gadolinium enhancement (LGE)
KW - cardiovascular magnetic resonance
KW - free-breathing
KW - motion correction
KW - outer volume suppression
KW - stack-of-spirals imaging
UR - http://www.scopus.com/inward/record.url?scp=84964683927&partnerID=8YFLogxK
U2 - 10.1002/mrm.26234
DO - 10.1002/mrm.26234
M3 - Article
C2 - 27122450
AN - SCOPUS:84964683927
SN - 0740-3194
VL - 77
SP - 1533
EP - 1543
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 4
ER -