Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells

Ingyu Choi; Kyungjong Kim; Youngmi Kim; Mi Jin Park; Yun Sil Lee; Dooil Jeoung

Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells

Ingyu Choi, Kyungjong Kim, Youngmi Kim, Mi Jin Park, Yun Sil Lee, Dooil Jeoung

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Allergic inflammation results from stimulation of β-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of β-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.

Original language	English
Pages (from-to)	1747-1752
Number of pages	6
Journal	Journal of Microbiology and Biotechnology
Volume	16
Issue number	11
State	Published - Nov 2006

Keywords

Allergic inflammation
Calcium influx
Chamaecyparis obtusa
ERK
Reactive oxygen species
β-hexosaminidase

Cite this

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title = "Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells",

abstract = "Allergic inflammation results from stimulation of β-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of β-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.",

keywords = "Allergic inflammation, Calcium influx, Chamaecyparis obtusa, ERK, Reactive oxygen species, β-hexosaminidase",

author = "Ingyu Choi and Kyungjong Kim and Youngmi Kim and Park, {Mi Jin} and Lee, {Yun Sil} and Dooil Jeoung",

year = "2006",

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pages = "1747--1752",

journal = "Journal of Microbiology and Biotechnology",

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T1 - Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells

AU - Choi, Ingyu

AU - Kim, Kyungjong

AU - Kim, Youngmi

AU - Park, Mi Jin

AU - Lee, Yun Sil

AU - Jeoung, Dooil

PY - 2006/11

Y1 - 2006/11

N2 - Allergic inflammation results from stimulation of β-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of β-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.

AB - Allergic inflammation results from stimulation of β-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of β-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.

KW - Allergic inflammation

KW - Calcium influx

KW - Chamaecyparis obtusa

KW - ERK

KW - Reactive oxygen species

KW - β-hexosaminidase

UR - http://www.scopus.com/inward/record.url?scp=33845579120&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33845579120

SN - 1017-7825

VL - 16

SP - 1747

EP - 1752

JO - Journal of Microbiology and Biotechnology

JF - Journal of Microbiology and Biotechnology

IS - 11

ER -

Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells

Abstract

Keywords

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