Fractions of Chamaecyparis obtusa display antiallergic effect in RBL2H3 cells

Ingyu Choi, Kyungjong Kim, Youngmi Kim, Mi Jin Park, Yun Sil Lee, Dooil Jeoung

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Allergic inflammation results from stimulation of β-hexosaminidase secretion, increased calcium influx, and activation of MAPK pathways. Some fractions of Chamaecyparis obtusa decreased secretion of β-hexosaminidase, calcium influx, ROS, and phosphorylation of ERK. These results suggest that Chamaecyparis obtusa would be valuable for development of allergy therapeutics.

Original languageEnglish
Pages (from-to)1747-1752
Number of pages6
JournalJournal of Microbiology and Biotechnology
Issue number11
StatePublished - Nov 2006


  • Allergic inflammation
  • Calcium influx
  • Chamaecyparis obtusa
  • ERK
  • Reactive oxygen species
  • β-hexosaminidase


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