Focal parenchymal lung lesions showing a potential of false-positive and false-negative interpretations on integrated PET/CT

Shine Shim Sung, Kyung Soo Lee, Byung Tae Kim, Young Choi Joon, Jin Chung Myung, Jeong Lee Eun

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

OBJECTIVE. We describe a number of benign focal lung lesions with increased 18F-FDG uptake that simulate lung cancer and malignant lesions that lead to false-negatives due to little 18F-FDG uptake on integrated PET/CT images. CONCLUSION. The integration of clinical history, morphologic findings of lung parenchymal lesions on the CT component, and metabolic activities on the PET component of integrated PET/CT can help reduce false interpretation of the study. A lung biopsy may be needed for lesions showing increased 18F-FDG uptake on PET for tissue confirmation irrespective of their morphology on CT.

Original languageEnglish
Pages (from-to)639-648
Number of pages10
JournalAmerican Journal of Roentgenology
Volume186
Issue number3
DOIs
StatePublished - Mar 2006

Keywords

  • F-FDG uptake
  • Lung
  • Lung cancer
  • Lung diseases
  • PET/CT

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