Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

Alain S. Leutou; Inho Yang; Tu Cam Le; Dongyup Hahn; Kyung Min Lim; Sang Jip Nam; William Fenical

doi:10.1038/s41429-018-0033-3

Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

Alain S. Leutou, Inho Yang, Tu Cam Le, Dongyup Hahn, Kyung Min Lim, Sang Jip Nam, William Fenical

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.

Original language	English
Pages (from-to)	609-612
Number of pages	4
Journal	Journal of Antibiotics
Volume	71
Issue number	6
DOIs	https://doi.org/10.1038/s41429-018-0033-3
State	Published - 1 Jun 2018

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© 2018 The Author(s) under exclusive licence to the Japan Antibiotics Research Association.

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abstract = "A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.",

author = "Leutou, {Alain S.} and Inho Yang and Le, {Tu Cam} and Dongyup Hahn and Lim, {Kyung Min} and Nam, {Sang Jip} and William Fenical",

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AU - Leutou, Alain S.

AU - Yang, Inho

AU - Le, Tu Cam

AU - Hahn, Dongyup

AU - Lim, Kyung Min

AU - Nam, Sang Jip

AU - Fenical, William

PY - 2018/6/1

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AB - A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.

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Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

Abstract

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