Fluvirucin B6, a new macrolactam isolated from a marine-derived actinomycete of the genus Nocardiopsis

Alain S. Leutou, Inho Yang, Tu Cam Le, Dongyup Hahn, Kyung Min Lim, Sang Jip Nam, William Fenical

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.

Original languageEnglish
Pages (from-to)609-612
Number of pages4
JournalJournal of Antibiotics
Volume71
Issue number6
DOIs
StatePublished - 1 Jun 2018

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