TY - JOUR
T1 - Fluorescent sensing of triphosphate nucleotides via anthracene derivatives
AU - Kim, Ha Na
AU - Moon, Jong Hun
AU - Kim, Sook Kyung
AU - Kwon, Ji Young
AU - Jang, Yun Jung
AU - Lee, Jin Yong
AU - Yoon, Juyoung
PY - 2011/5/20
Y1 - 2011/5/20
N2 - A nucleotide is composed of a nucleobase, a five-carbon sugar, and phosphate groups. Recognition of these three sites can provide useful information for the development of selective fluorescent receptors for a specific nucleotide. In this paper, anthracene derivatives with two imidazolium groups at the 1,8- and 9,10-positions, quaternary ammonium groups, or the boronic acid group were examined for the recognition of nucleotides, such as ATP, GTP, CTP, TTP, UTP, ADP, and AMP, via fluorescence changes. The anthracene group provides the interaction between the bases of the nucleotides. The imidazolium and quaternary ammonium groups induce hydrogen bonding interactions with the phosphate groups of the nucleotides. The boronic acid group can interact with the ribose of the nucleotides.
AB - A nucleotide is composed of a nucleobase, a five-carbon sugar, and phosphate groups. Recognition of these three sites can provide useful information for the development of selective fluorescent receptors for a specific nucleotide. In this paper, anthracene derivatives with two imidazolium groups at the 1,8- and 9,10-positions, quaternary ammonium groups, or the boronic acid group were examined for the recognition of nucleotides, such as ATP, GTP, CTP, TTP, UTP, ADP, and AMP, via fluorescence changes. The anthracene group provides the interaction between the bases of the nucleotides. The imidazolium and quaternary ammonium groups induce hydrogen bonding interactions with the phosphate groups of the nucleotides. The boronic acid group can interact with the ribose of the nucleotides.
UR - http://www.scopus.com/inward/record.url?scp=79956097506&partnerID=8YFLogxK
U2 - 10.1021/jo2000836
DO - 10.1021/jo2000836
M3 - Article
C2 - 21500816
AN - SCOPUS:79956097506
SN - 0022-3263
VL - 76
SP - 3805
EP - 3811
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 10
ER -