Fluorescent chemosensors that signal carbohydrates in aqueous solution: a novel mechanism for signal transduction is required and found

Juyoung Yoon, Anthony W. Czarnik

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

2-Anthrylboronic acid (pKa 8.8) displays decreased fluorescence in the boronate form compared with its boronic acid form, which we attribute to photoinduced electron transfer. When the boronic acid complexes to polyols such as fructose, the pKa of the complex decreases; thus, the fluorimetrically determined pKa of the 2-anthrylboronic acid:fructose borate ester is 5.9. These properties combined permit polyol complexation in water to be observed spectrofluorimetrically, which has not been reported previously. Fructose binds with a fluorimetrically determined Kd of 3.7 mM.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsRobert A. Lieberman
PublisherPubl by Society of Photo-Optical Instrumentation Engineers
Pages87-91
Number of pages5
ISBN (Print)0819409758
StatePublished - 1993
EventChemical, Biochemical, and Environmental Fiber Sensors IV - Boston, MA, USA
Duration: 8 Sep 19929 Sep 1992

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1796
ISSN (Print)0277-786X

Conference

ConferenceChemical, Biochemical, and Environmental Fiber Sensors IV
CityBoston, MA, USA
Period8/09/929/09/92

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