Fluorescent chemosensing of catechol and catecholamines in water

Juyoung Yoon, Anthony W. Czarnik

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

It has been known for almost 35 years that catechol complexes reversibly to boronic acids. We observe that 2-anthrylboronic acid complexes catechol in water with Kd 330 μM and concomitant 20-fold reduction in fluorescence intensity, l-DOPA and dopamine behave similarly, suggesting a mechanism for the development of real-time sensing schemes.

Original languageEnglish
Pages (from-to)267-271
Number of pages5
JournalBioorganic and Medicinal Chemistry
Volume1
Issue number4
DOIs
StatePublished - Oct 1993

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