FET-based nanobiosensors for the detection of smell and taste

Dongseok Moon, Yeon Kyung Cha, So ong Kim, Seongyeon Cho, Hwi Jin Ko, Tai Hyun Park

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Various nanobiosensors composed of biomaterials and nanomaterials have been developed, due to their demonstrated advantage of showing high performance. Among various biomaterials for biological recognition elements of the nanobiosensor, sensory receptors, such as olfactory and taste receptors, are promising biomaterials for developing nanobiosensors, because of their high selectivity to target molecules. Field-effect transistors (FET) with nanomaterials such as carbon nanotube (CNT), graphene, and conducting polymer nanotube (CPNT), can be combined with the biomaterials to enhance the sensitivity of nanobiosensors. Recently, many efforts have been made to develop nanobiosensors using biomaterials, such as olfactory receptors and taste receptors for detecting various smells and tastes. This review focuses on the biomaterials and nanomaterials used in nanobiosensor systems and studies of various types of nanobiosensor platforms that utilize olfactory receptors and taste receptors which could be applied to a wide range of industrial fields, including the food and beverage industry, environmental monitoring, the biomedical field, and anti-terrorism.

Original languageEnglish
Pages (from-to)1159-1167
Number of pages9
JournalScience China Life Sciences
Issue number8
StatePublished - 1 Aug 2020

Bibliographical note

Publisher Copyright:
© 2020, Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature.


  • field-effect transistor (FET)
  • nanobiosensor
  • olfactory receptor
  • taste receptor


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