Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure

Chung Jong Kim; Seung Ji Kang; Doran Yoon; Myung Jin Lee; Moonsuk Kim; Kyoung Ho Song; Hee Chang Jang; Sook In Jung; Eu Suk Kim; Hong Bin Kim; Myoung Don Oh; Kyung Hwa Park; Nam Joong Kim

doi:10.1128/AAC.04949-14

Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure

Chung Jong Kim, Seung Ji Kang, Doran Yoon, Myung Jin Lee, Moonsuk Kim, Kyoung Ho Song, Hee Chang Jang, Sook In Jung, Eu Suk Kim, Hong Bin Kim, Myoung Don Oh, Kyung Hwa Park, Nam Joong Kim

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

We conducted a retrospective cohort study to evaluate factors influencing tissue culture positivity in patients with pyogenic vertebral osteomyelitis exposed to antibiotics before diagnosis. Tissue culture was positive in 48.3% (28/58) of the patients, and the median antibiotic-free period was 1.5 days (range, 0.7 to 5.7 days). In a multivariate analysis, a higher C-reactive protein (CRP) level (adjusted odds ratio [aOR], 1.18; 95% confidence interval, 1.07 to 1.29) and open surgical biopsy (aOR, 6.33; 95% confidence interval, 1.12 to 35.86) were associated with tissue culture positivity.

Original language	English
Pages (from-to)	2470-2473
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	59
Issue number	4
DOIs	https://doi.org/10.1128/AAC.04949-14
State	Published - 1 Apr 2015

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Publisher Copyright:
Copyright © 2015, American Society for Microbiology.

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Kim, C. J., Kang, S. J., Yoon, D., Lee, M. J., Kim, M., Song, K. H., Jang, H. C., Jung, S. I., Kim, E. S., Kim, H. B., Oh, M. D., Park, K. H., & Kim, N. J. (2015). Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure. Antimicrobial Agents and Chemotherapy, 59(4), 2470-2473. https://doi.org/10.1128/AAC.04949-14

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abstract = "We conducted a retrospective cohort study to evaluate factors influencing tissue culture positivity in patients with pyogenic vertebral osteomyelitis exposed to antibiotics before diagnosis. Tissue culture was positive in 48.3% (28/58) of the patients, and the median antibiotic-free period was 1.5 days (range, 0.7 to 5.7 days). In a multivariate analysis, a higher C-reactive protein (CRP) level (adjusted odds ratio [aOR], 1.18; 95% confidence interval, 1.07 to 1.29) and open surgical biopsy (aOR, 6.33; 95% confidence interval, 1.12 to 35.86) were associated with tissue culture positivity.",

author = "Kim, {Chung Jong} and Kang, {Seung Ji} and Doran Yoon and Lee, {Myung Jin} and Moonsuk Kim and Song, {Kyoung Ho} and Jang, {Hee Chang} and Jung, {Sook In} and Kim, {Eu Suk} and Kim, {Hong Bin} and Oh, {Myoung Don} and Park, {Kyung Hwa} and Kim, {Nam Joong}",

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AU - Kang, Seung Ji

AU - Yoon, Doran

AU - Lee, Myung Jin

AU - Kim, Moonsuk

AU - Song, Kyoung Ho

AU - Jang, Hee Chang

AU - Jung, Sook In

AU - Kim, Eu Suk

AU - Kim, Hong Bin

AU - Oh, Myoung Don

AU - Park, Kyung Hwa

AU - Kim, Nam Joong

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Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure

Abstract

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