Facility-Based and Home-Based Multidomain Interventions Including Cognitive Training, Exercise, Diet, Vascular Risk Management, and Motivation for Older Adults: A Randomized Controlled Feasibility Trial

So Young Moon, Chang Hyung Hong, Jee Hyang Jeong, Yoo Kyoung Park, Hae Ri Na, Hong Sun Song, Byeong C. Kim, Kyung Won Park, Hee Kyung Park, Muncheong Choi, Sun Min Lee, Buong O. Chun, Seong Ho Koh, Sun Ah Park, Hyun Hee Park, Jeong Hwa Jin, Eun Hye Lee, Sue Min Kim, Song Mi Han, Jun Seok KimJungsoon Ha, Seong Hye Choi

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We aimed to evaluate the feasibility of multidomain intervention (MI) tailored to the Korean context. In an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI (FMI; n=51), the home-based MI (HMI; n=51), or the control group receiving general health advice (n=50). The 24- week intervention comprised vascular risk management, cognitive training, social activity, physical exercise, nutrition guidance, and motivational enhancement. The FMI participants performed all intervention programs at a facility three times a week. The HMI participants performed some programs at a facility once every 1-2 weeks and performed others at home. The primary outcome was feasibility measured through retention, adherence, and at least no differences from the control group in the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). In the FMI and HMI groups, the retention rates were 88.2% and 96.1%, and adherence to the intervention was 94.5% and 96.8%, respectively. The RBANS total scale index score improved significantly in the FMI (5.46 ± 7.50, P = 0.004) and HMI (5.50 ± 8.14, P = 0.004) groups compared to the control group (-0.74 ± 11.51). The FMI and HMI are feasible and there are indicators of efficacy.

Original languageEnglish
Pages (from-to)15898-15916
Number of pages19
JournalAging
Volume13
Issue number12
DOIs
StatePublished - 30 Jun 2021

Keywords

  • dementia
  • feasibility
  • lifestyle
  • prevention
  • randomized controlled trial

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