Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

Luling Wu; Chusen Huang; Ben P. Emery; Adam C. Sedgwick; Steven D. Bull; Xiao Peng He; He Tian; Juyoung Yoon; Jonathan L. Sessler; Tony D. James

doi:10.1039/c9cs00318e

Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

Luling Wu, Chusen Huang, Ben P. Emery, Adam C. Sedgwick, Steven D. Bull, Xiao Peng He, He Tian, Juyoung Yoon, Jonathan L. Sessler, Tony D. James

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Review article › peer-review

576 Scopus citations

Abstract

In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.

Original language	English
Pages (from-to)	5110-5139
Number of pages	30
Journal	Chemical Society Reviews
Volume	49
Issue number	15
DOIs	https://doi.org/10.1039/c9cs00318e
State	Published - 7 Aug 2020

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© The Royal Society of Chemistry.

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title = "F{\"o}rster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents",

abstract = "In this tutorial review, we will explore recent advances in the construction and application of F{\"o}rster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.",

author = "Luling Wu and Chusen Huang and Emery, {Ben P.} and Sedgwick, {Adam C.} and Bull, {Steven D.} and He, {Xiao Peng} and He Tian and Juyoung Yoon and Sessler, {Jonathan L.} and James, {Tony D.}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

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doi = "10.1039/c9cs00318e",

language = "English",

volume = "49",

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AU - Wu, Luling

AU - Huang, Chusen

AU - Emery, Ben P.

AU - Sedgwick, Adam C.

AU - Bull, Steven D.

AU - He, Xiao Peng

AU - Tian, He

AU - Yoon, Juyoung

AU - Sessler, Jonathan L.

AU - James, Tony D.

PY - 2020/8/7

Y1 - 2020/8/7

N2 - In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.

AB - In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.

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U2 - 10.1039/c9cs00318e

DO - 10.1039/c9cs00318e

M3 - Review article

C2 - 32697225

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SN - 0306-0012

VL - 49

SP - 5110

EP - 5139

JO - Chemical Society Reviews

JF - Chemical Society Reviews

IS - 15

ER -

Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents

Abstract

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