Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

Ala Jo; Jongmin Park; Seung Bum Park

doi:10.1039/c3cc41529e

Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

Ala Jo
, Jongmin Park
, Seung Bum Park

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.

Original language	English
Pages (from-to)	5138-5140
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	45
DOIs	https://doi.org/10.1039/c3cc41529e
State	Published - 9 May 2013

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title = "Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells",

abstract = "Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.",

author = "Ala Jo and Jongmin Park and Park, \{Seung Bum\}",

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AU - Jo, Ala

AU - Park, Jongmin

AU - Park, Seung Bum

PY - 2013/5/9

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N2 - Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.

AB - Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.

UR - https://www.scopus.com/pages/publications/84877819842

U2 - 10.1039/c3cc41529e

DO - 10.1039/c3cc41529e

M3 - Article

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VL - 49

SP - 5138

EP - 5140

JO - Chemical Communications

JF - Chemical Communications

IS - 45

ER -

Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

Abstract

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