@inproceedings{25bb86ff07584367b6aaedb7d449cbab,
title = "Exosome-specific dual-patterned immuno-filtration (EXODIF) devices for the rapid capture and efficient release of circulating exosome from cancer patients' blood",
abstract = "We present a microfluidics device for the capture and release of circulating exosome from blood. The EXODIF, composed of two distinct immuno-patterned layers, is capable to enhance binding chance between antibody and exosome and generates mechanical whirling; thus achieving high-throughput and specific exosome isolation. The device performance was verified using blood from cancer patients and healthy donors, revealed that cancer patient show significantly higher exosome level compared to healthy donors after electron microscopy and nanoparticle tracking analysis. This simple and fast exosome isolation is appropriate for exosome-based cancer diagnostics and may help to elucidate the function of exosome in cancer.",
keywords = "Cancer, Dual immuno-patterns, Exosome, Extracellular vesicles, Isolations",
author = "Kang, {Y. T.} and Kim, {Y. J.} and J. Bu and I. Doh and Cho, {Y. H.} and Han, {S. W.} and Moon, {B. I.}",
note = "Funding Information: This research was supported by the Converging Research Center Program funded by the Ministry of Science, ICT and Future Planning (Project No. 2015054201); null ; Conference date: 09-10-2016 Through 13-10-2016",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "317--318",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
}
