TY - JOUR
T1 - Evaluation of skeletal maturity score for Korean children and the standard for comparison of bone age and chronological age in normal children
AU - Oh, Yoonjin
AU - Lee, Rena
AU - Kim, Hae Soon
N1 - Funding Information:
This research was supported in part by National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (2009-0085999) and in part by Ministry of Knowledge Economy (Grant No 10035495).
PY - 2012/4/1
Y1 - 2012/4/1
N2 - Background: The growth assessment of bone age (BA) is an essential feature in diagnosing various diseases in children. In the clinic, the Tanner and Whitehouse (TW3) method and the Greulich-Pyle (GP) method are used to estimate bone age. Because those methods were developed for foreign children, it is necessary to evaluate the applicability of those methods to Koreans. Objectives: This study was designed (1) to compare the skeletal maturity score (SMS) in Koreans to the SMS in foreign children, and (2) to establish a correlation between the BA and chronological age (CA) on the basis of gender and age in normal Korean children. Material and methods: We estimated the SMS and BA for 378 healthy children (141 boys and 237 girls) who visited the pediatrics clinic in Ewha Womans University Mokdong Hospital (Seoul, Korea) from 2000 to 2009. The SMS and BA were estimated using the TW3 and GP methods. Results: The SMS in Koreans was higher than in foreign children, and on average, the BA measured by both methods was higher than the CA. The correlation between the BA and CA were different according to gender and age. Conclusions: We suggest that there are differences between the SMS in Korean and foreign children and between the BA and CA. Therefore, the results can be used in evaluating the skeletal maturity of Koreans, and a correlation between the BA and CA would be a useful reference in diagnosis.
AB - Background: The growth assessment of bone age (BA) is an essential feature in diagnosing various diseases in children. In the clinic, the Tanner and Whitehouse (TW3) method and the Greulich-Pyle (GP) method are used to estimate bone age. Because those methods were developed for foreign children, it is necessary to evaluate the applicability of those methods to Koreans. Objectives: This study was designed (1) to compare the skeletal maturity score (SMS) in Koreans to the SMS in foreign children, and (2) to establish a correlation between the BA and chronological age (CA) on the basis of gender and age in normal Korean children. Material and methods: We estimated the SMS and BA for 378 healthy children (141 boys and 237 girls) who visited the pediatrics clinic in Ewha Womans University Mokdong Hospital (Seoul, Korea) from 2000 to 2009. The SMS and BA were estimated using the TW3 and GP methods. Results: The SMS in Koreans was higher than in foreign children, and on average, the BA measured by both methods was higher than the CA. The correlation between the BA and CA were different according to gender and age. Conclusions: We suggest that there are differences between the SMS in Korean and foreign children and between the BA and CA. Therefore, the results can be used in evaluating the skeletal maturity of Koreans, and a correlation between the BA and CA would be a useful reference in diagnosis.
KW - bone age
KW - Greulich and Pyle skeletal maturity
KW - Tanner and Whitehouse
UR - http://www.scopus.com/inward/record.url?scp=84861622747&partnerID=8YFLogxK
U2 - 10.1515/jpem-2012-0028
DO - 10.1515/jpem-2012-0028
M3 - Article
C2 - 22768657
AN - SCOPUS:84861622747
SN - 0334-018X
VL - 25
SP - 279
EP - 284
JO - Journal of Pediatric Endocrinology and Metabolism
JF - Journal of Pediatric Endocrinology and Metabolism
IS - 3-4
ER -