Evaluation of Mechanical and Thermal Properties of Hydroxyapatite-levan Composite Bone Graft

Younghoon Song, Kye Joo, Jeong Hyun Seo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Biodegradable materials have been received great attention as bone graft substitutes for bone regeneration and tissue engineering. However, their low mechanical property remains a major challenge for the use in load-bearing applications. Here, we developed mechanically reinforced composite scaffold containing adhesive levan as a binder for sintered hydroxyapatite (sHAp) and then examined the mechanical and thermal properties of the composite scaffold. We found that sHAp-levan composite scaffold exhibited remarkably enhanced mechanical strength, which is similar to that of polymethyl methacrylate (PMMA) bone cement. This composite scaffold can be utilized as a promising bone graft for bone regeneration and tissue engineering.

Original languageEnglish
Pages (from-to)201-207
Number of pages7
JournalBiotechnology and Bioprocess Engineering
Volume26
Issue number2
DOIs
StatePublished - Apr 2021

Keywords

  • bone graft
  • composite scaffold
  • hydroxyapatite
  • levan
  • sintering

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