Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

Kyung Eun Han, Sang Chul Yoon, Ji Min Ahn, Sang Min Nam, R. Doyle Stulting, Eung Kweon Kim, Kyoung Yul Seo

Research output: Contribution to journalArticlepeer-review

138 Scopus citations


• Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

Original languageEnglish
Pages (from-to)1144-1150.e1
JournalAmerican Journal of Ophthalmology
Issue number6
StatePublished - Jun 2014

Bibliographical note

Funding Information:
All authors have completed and submitted the ICMJE form for disclosure for potential conflicts of interest, and none were reported. This study was supported by a grant from the Korea Healthcare technology R&D Project , Ministry of Health & Welfare , Republic of Korea (Grant No. A121861 ). Involved in design of study (K.E.H., K.Y.S); Conduct of study (K.E.H., S.C.Y., K.Y.S); Collection, management, analysis, and interpretation of data (K.E.H., S.C.Y., S.M.N., J.M.A., K.Y.S); Preparation of manuscript (K.E.H., K.Y.S); Critical revision of article; (K.E.H., S.M.N., R.D.S., K.Y.S.); Final approval of manuscript (K.E.H., R.D.S., E.K.K., K.Y.S).


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