TY - JOUR
T1 - Evaluation of dry eye and meibomian gland dysfunction after cataract surgery
AU - Han, Kyung Eun
AU - Yoon, Sang Chul
AU - Ahn, Ji Min
AU - Nam, Sang Min
AU - Stulting, R. Doyle
AU - Kim, Eung Kweon
AU - Seo, Kyoung Yul
N1 - Funding Information:
All authors have completed and submitted the ICMJE form for disclosure for potential conflicts of interest, and none were reported. This study was supported by a grant from the Korea Healthcare technology R&D Project , Ministry of Health & Welfare , Republic of Korea (Grant No. A121861 ). Involved in design of study (K.E.H., K.Y.S); Conduct of study (K.E.H., S.C.Y., K.Y.S); Collection, management, analysis, and interpretation of data (K.E.H., S.C.Y., S.M.N., J.M.A., K.Y.S); Preparation of manuscript (K.E.H., K.Y.S); Critical revision of article; (K.E.H., S.M.N., R.D.S., K.Y.S.); Final approval of manuscript (K.E.H., R.D.S., E.K.K., K.Y.S).
PY - 2014/6
Y1 - 2014/6
N2 - • Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.
AB - • Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.
UR - http://www.scopus.com/inward/record.url?scp=84901790785&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2014.02.036
DO - 10.1016/j.ajo.2014.02.036
M3 - Article
C2 - 24561172
AN - SCOPUS:84901790785
SN - 0002-9394
VL - 157
SP - 1144-1150.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 6
ER -