Evaluation of bipolar radiofrequency ablation for occluded self-expandable metal stents in the bile duct: In vivo and in vitro study

Won Jae Yoon, Yong Tae Kim, Ebubekir S. Daglilar, Mari Mino-Kenudson, William R. Brugge

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Background and aims: Endobiliary radiofrequency ablation (RFA) has been used to treat occluded self-expandable metal stents (SEMSs). The aim of this study was to determine the characteristics of bipolar RFA in occluded SEMSs using both in vivo and in vitro models. Methods: For the in vivo study, uncovered SEMSs were deployed in the bile ducts of three pigs; another pig was used as the control. RFA was performed at 10 W for 90 seconds. The bile duct was examined for histological changes. For the in vitro simulation of tissue ingrowth in SEMSs, RFA at 10 W for 30 seconds was performed on SEMS-occlusion polyacrylamide-gel phantoms. Results: The ablation depth was markedly reduced in the stented porcine bile duct. RFA of uncovered SEMS-occlusion gel phantoms resulted in early termination of RFA when the coagulated area contacted the SEMS. This phenomenon was not observed in RFA of the covered SEMS-occlusion gel phantoms. Conclusions: The presence of SEMSs attenuated the effect of bipolar endobiliary RFA. Tumorous tissue outside the SEMS is unlikely to be affected.

Original languageEnglish
Pages (from-to)1167-1170
Number of pages4
JournalEndoscopy
Volume47
Issue number12
DOIs
StatePublished - 1 Dec 2015

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