The present study evaluated the effectiveness of a sexual abuse prevention program for children with intellectual disabilities. Three children with mild to moderate intellectual disabilities participated in the study. They were taught skills relative to identifying body parts and discrimination between appropriate and inappropriate situations, refusal skills (verbal refusing and leaving situations), and reporting skills through this program. A multiple probe across participants design was used to determine the effects of the program. Results demonstrated that the program was effective for teaching the skills to all three children with intellectual disabilities. In addition, these skills generalized in probes conducted in real-life settings and maintained at 10-week follow-up probes.