Endoscopic ultrasonography (EUS) is a highly sensitive test for the detection of cystic lesions of the pancreas. EUS-guided fine-needle aspiration provides cystic fluid for analysis of a variety of tumor markers. The level of carcinoembryonic antigen in the cystic fluid has been reported to be the most accurate marker to distinguish mucinous and nonmucinous pancreatic cystic lesions. Cystic fluid cytology, although the sensitivity is relatively low due to lack of cellular content, is the most accurate test for the diagnosis of a malignant pancreatic cystic lesion. Advances in DNA analysis of pancreatic cystic fluid may provide additional diagnostic information on the lesions.
|Title of host publication
|Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors
|Subtitle of host publication
|Diagnosis and Management
|Number of pages
|Published - 7 Apr 2015
Bibliographical notePublisher Copyright:
© 2015 by John Wiley & Sons, Ltd. All rights reserved.
- Carcinoembryonic antigen
- DNA analysis
- Endoscopic ultrasound-guided fine-needle aspiration
- Pancreatic cystic lesion