Electrospun poly (lactic-co-glycolic acid)(PLGA) microparticles for controlled drug delivery system

J. Y. Lee, M. H. Lee, W. H. Park, B. M. Min, S. J. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The use of electrospinning technique for the fabrication of poly(lactic-co-glycolic acid) (PLGA) microparticles for drug delivery system and coating materials in order to reduce initial burst release was discussed. It was observed that the morphology of PLGA microparticles was influenced by parameters such as polymer concentration, electrospinning voltage and air gap distance. It was found that the initial burst of PLLA particles could be reduced by coating with PLGA microparticles. The results show that electrospinning of PLGA microparticles could be used as controlled drug delivery system for sustained release and release controlling modality.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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