An efficient method for the synthesis of optically active 2-substituted 2,3-dihydro-4-quinolones has been developed. The key features include the introduction of a chiral side chain and the construction of quinolone skeleton by Mitsunobu alkylation and hydroarylation, respectively.
Bibliographical noteFunding Information:
This work was supported by the Ewha Womans University Research Grant of 2005.
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