Abstract
Silkworm hemolymph when added at 5% (v/v) to medium increased the production of recombinant β-galactosidase in Spodoptera frugipera/Autographa californica nuclear polyhedrosis virus (AcNPV) system by 4.5-fold. Silkworm hemolymph also increased the host cell longevity by two-fold. Viability of the host cell was maintained at a constant level for 6 days after baculovirus infection in the medium containing 5% silkworm hemolymph, while host cells began to die 3 days after infection in the medium without hemolymph.
Original language | English |
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Pages (from-to) | 1087-1091 |
Number of pages | 5 |
Journal | Biotechnology Letters |
Volume | 19 |
Issue number | 11 |
DOIs | |
State | Published - 1997 |
Bibliographical note
Funding Information:This work was supported by ‘95 biochemical engineering supporting program (the Korean Ministry of Education) and Sericulture & Insect Research Institute.