Introduction To prove objective effect of using mechanical device for immobilization of pediatric patient during voiding cystourethrogram (VCUG) compare immobilization by hand-holding. Methods This study included 77 patients, who underwent VCUG in our center from April to October 2017, who had a clinically suspicious urinary tract infection. Patients were classified into one of two groups based on whether examination was done before (Group A) or after (Group B) adaptation of immobilization device. Patient-related data, image quality related score and dose-related data were collected and compared between two groups. Results Group A included 36 patients and group B included 41. Patient related data including mean age, sex, body weight and height didn’t show significant difference between two groups (p > 0.05 for all). Among the image quality scoring, overall image quality, motion artifact, showed significant difference between two groups with improved inadequate timing and centering after adaptation of immobilization device. Dose related data showed significantly decreased shot number, mean fluoroscopic time with decreased mean dose area product (DAP) value and effective dose after adaptation of immobilization device (p < 0.05 for all). Conclusion Adaptation of immobilization device can improve overall image quality with decreased motion artifact and improved centering and timing with even shot number, mean fluoroscopic time with decreased mean DAP value and effective dose.