The aim of this study was to investigate the effects of dried garlic flesh and dried juice of garlic flesh on the body fat and lipid metabolism of 9-month-old rats with diet-induced obesity. For 8 weeks, the rats were fed either a control diet or experimental diets containing 3 or 5%(w/w) of dried, powdered garlic flesh or garlic juice. In our study, body weight gains and calorie efficiency ratios were the lowest in 5% dried garlic flesh treatment. Hepatic diacylglycerol acyltransferase (DGAT) activities were inhibited relatively to the control for the dried garlic flesh treatments. Fecal total lipid excretion, plasma total lipid, and triglyceride concentrations were significantly improved through the 5% dried garlic flesh treatment. In conclusion, garlic consumption reduced the body fat and improved lipid profile in rats. Especially, consumption of dried garlic flesh was turned out to be more effective than the intake of dried garlic juice.
Bibliographical noteFunding Information:
Acknowledgments This work was supported by grants from Daesang Co., Ltd. and the second stage of the Brain Korea 21 project.
- Body fat
- Diacylglycerol acyltransferase activity